Heat the oven to 425°F with a rack in the middle. Line a large rimmed sheet pan with parchment paper.
Toss the broccoli with 1 tbsp olive oil and 1/4 tsp salt, spread it in a single layer, and roast for 10 minutes, until bright green.
Meanwhile, whisk the remaining 1 tbsp olive oil with the lemon juice, Dijon, garlic, honey, 1/4 tsp salt and the pepper in a small bowl.
Nestle the salmon fillets among the broccoli, skin-side down, and brush each fillet with half of the lemon-Dijon mixture.
Roast for 10-12 minutes, until the salmon flakes easily with a fork and reaches 145°F in the center; check early if your fillets are thin.
Spoon the remaining lemon-Dijon mixture and pan juices over the salmon, squeeze with lemon wedges, and serve.